State highways 17, 33, 86, 88 pass through Mysore(Mysooru) connecting it to nearby cities. The existing four-lane road linking Mysore(Mysooru) to Bangalore is being upgraded to a six-lane highway, thus significantly reducing the commute time. Mysore(Mysooru) is the railway junction for the district, and rail lines connect Mysore(Mysooru) city to Bangalore to the northeast via Mandya, the rail junction at Hassan to the northwest, and Chamarajanagar via Nanjangud to the south east.

The nearest airport is at Bangalore. The Mandkalli Airport, approximately 4 miles from the city, is currently inoperative, although paragliding and, occasionally, aeroplane rides are offered at this location. A memorandum of understanding is expected to be signed by the Karnataka government and the Airports Authority of India, leading to the redesign and extension of the airport.

Mysore(Mysooru) has intra-city, inter-city and suburban public bus transportation. Traditional means of transport available in other Indian cities like Autorickshaws and Taxis are also available. Tongas (horse drawn carriages) are also available, but usage is declining.